Globalization has exported more than goods and higher living standards. It’s also exported urbanization, and with it, the kinds of diets and lifestyles that factor into chronic disease has gone global. Since 1987, there has been a 400% increase in obesity in the developing world. That means the governments of these countries are now presented with an all too familiar health challenge: how to do a lot more, with less. But with new challenges comes new opportunity, measured in trillions of dollars and the quality of billions of lives, and it’s an opportunity that will likely be answered in completely new ways. The tectonic plates of global health are shifting. In this lively discussion, we ask the question, as healthcare professionals, as innovators, as global citizens, How can we help people lead healthier lives, globally?